The Lupus Study's FAQ's
1) Why do you need blood from family members who do not have SLE?
Because we are trying to determine the inheritance patterns of genes through generations in families, we need parents, grandparents, and some aunts, uncles, brothers, and sisters to participate. The specific family members that qualify for participation are determined by their blood relationship to the lupus patient(s).
There are several possible reasons:
Developing a cure for SLE is extremely difficult because we don't know what the cause is, and there are many aspects of the disease we don't understand very well. Therefore, research is extremely important. Your participation in studies such as ours is a great way to help. Some additional ideas for ways you can help are listed below:
Simply, no. This rumor surfaced in 1992 when the Food and Drug Administration banned silicone breast implants due to a high occurrence of rupture as well as a reported increase in autoimmune diseases such as fibromyalgia, rheumatoid arthritis, and lupus. In 1994, The American College of Rheumatology conducted the most comprehensive studies to date and found no connection between silicone breast implants and lupus or any other connective tissue disease.
The pattern of inheritance is highly unpredictable. Sometimes the genes will show up in every generation, sometimes the genes skip one or more generations. Researchers are working to determine why this occurs, but for now it remains a mystery.
There are four main types of lupus:
Scientific research is done by making comparisons. What is the best kind of person to compare with the lupus patients? Those with the most genetic differences from lupus patients work the best. These comparison participants (referred to by scientists as “controls”) are unrelated people with no known lupus in their families. With them we have the best chance to make the best comparison. return to Healthy Individuals...
No. There are several tests, commonly known as a lupus panel, that can indicate whether certain conditions are present in a patient. Tests can determine that the body is undergoing an autoimmune attack, but even the best test is only an indication and must be taken into consideration with other diagnostic methods.
The most commonly used syphilis tests screen for an antibody to the syphilis organism. Lupus patients sometimes have a very similar antibody. This similar antibody, the antiphospholipid antibody (aPL), can cause an incorrect positive result on a syphilis test. If the doctor suspects that the patient may not really have syphilis, he may choose to then run a different, more complicated and expensive test that checks specifically for the syphilis organism. If this test is negative, then the patient does not have syphilis and the result of the first test is considered to be a "false positive". A false-positive syphilis test in a person's medical history may be an indication of lupus.
Lupus Foundation of America (www.lupus.org) is a great site for general lupus information as well as finding lupus resources in your area.
National Institute for Arthritis and Musculoskeletal and Skin Diseases (NIAMS) (www.niams.nih.gov) contains general information about musculoskeletal diseases and is a good starting point for research. NIAMS is part of the National Institutes of Health (www.nih.gov).
Lupus Foundation of Northern California (www.saclupus.org) includes News and Education sections that make available some of the most detailed, thorough and up-to-date lupus information on the web.
SLE Foundation of New York (www.lupusny.org) is great for general information and provides information about the latest research developments.
American College of Rheumatology (ACR) (www.rheumatology.org) can be used to locate an ACR-accredited rheumatologist in your area.
Arthritis Foundation of America (www.arthritis.org) offers event news, nutrition tips and relationship advice for those dealing with chronic pain and any type of arthritis.
National Institute of Diabetes and Digestive and Kidney Disease (NIDDK) (www.niddk.nih.gov) provides patient information on kidney diseases and treatments.
Interested in Participating? See what Study Participation involves, email a Recruiter at
or call toll-free (in the USA, Canada, PR, VI) 1-888-655-8787 (1-888-OK-LUPUS)
LUPUS GENETIC STUDIES • OKLAHOMA MEDICAL RESEARCH FOUNDATION • 825 NE 13TH STREET MAILSTOP #5, OKLAHOMA CITY, OK 73104